Joshua McLane, Ph.D.
Deekshita is a senior, majoring in Quantitative Biology at UNC. She joined the Snider lab in early 2015 and has been involved in multiple projects, including analysis of post-translational modifications, cell culture, transfections, gene expression analysis, site-directed mutagenesis, imaging, and functional protein analysis. She is currently enrolled in an independent Biology research course and her project is aimed at investigating the role of site-specific CD73 glycosylation on subcellular localization and enzymatic function. Deekshita plans to pursue graduate training in Public Health.
Deekshita Ramanarayanan Undergraduate Research Assistant
Natasha completed her undergraduate studies in Biochemistry and Molecular Biology at Michigan State University, supported by the Loyse W. and Gordon H. Hueschen Science Scholarship. As a graduate student with Paul Hollenberg in the Pharmacology department at the University of Michigan (2004-2009), she studied cytochrome P450-mediated pathways of endocannabinoid metabolism. She was an NIDDK-funded post-doctoral fellow (2009-2011) and research investigator (2011-2014) with Bishr Omary in the Department of Molecular & Integrative Physiology at the University of Michigan, studying keratin intermediate filaments and mechanisms of liver injury. Natasha started her independent research program as Assistant Professor of Cell Biology and Physiology at UNC-CH in January 2015. She is also a full member of the Center for Gastrointestinal Biology and Disease (CGIBD).
Natasha Snider, Ph.D.
Melinda Lian, B.S.
Melinda completed her undergraduate studies in Biology and Chemistry at UNC-CH in December 2015 and has been working as a research technician in the Snider lab since graduation. Melinda is currently interviewing for Dental School admission and plans to enroll in a DDS program in the Fall of 2017. In the Snider lab she is investigating aging and diet-dependent biochemical changes on the properties of different tissue-specific intermediate filaments using mouse and human cells and tissues.
Megan is a senior at UNC Chapel Hill majoring in Biomedical and Health Sciences Engineering. She completed an Associate of Science: Pre-Engineering degree in 2015 at Wake Technical Community College prior to transferring to UNC. Her undergraduate studies have been supported through funding from GlaxoSmithKline and the North Carolina Space Grant. As a research assistant in the Snider lab she conducts projects related to mouse colony management and genotyping and liver injury studies. Megan is also a Teaching Assistant in the Department of Biomedical Engineering at UNC-CH. Megan plans to enroll in a PhD program to pursue medical device design and entrepreneurial endeavors, specifically in areas of under served patient populations.
Joshua completed his undergraduate studies in Biology at The State University of New York at Buffalo, supported by an academic merit scholarship. He pursued graduate studies with Lee Ligon in the Biology department, where he studied the cellular effects of physical and biological cues originating from the cellular microenvironment. His post-doctoral research in the Snider lab (joint with Hong Jin Kim, MD) is focused on constructing vectors for CD73 expression and purification for use in mouse models. The work will facilitate understanding of enzymatic and non-enzymatic CD73 mechanisms in liver disease and HCC.
Helen Willcockson, M.S.
Lab Manager and Research Associate
Marquet completed his undergraduate studies in Biology at Winthrop University. During his post-baccalaureate research experience at Washington University in St. Louis, he analyzed the roles of telomerase in stem cell function using human pluripotent stem cells as a model. His rotation project focuses on determining if a novel small molecule compound can alleviate disease-associated intermediate filament protein aggregation.
Undergraduate Research Assistant
in the Cell Biology and Physiology Department at UNC-Chapel Hill
Chloe is a junior at UNC Chapel Hill majoring in Biology and Global Studies. As a research assistant in the Snider lab, she assists with mouse colony management and genotyping. Chloe works closely with Helen to keep lab inventories updated, and interfaces with the Histology core facility to ensure timely and efficient completion of projects and sample analysis.
Marquet Minor, B.S.
Rachel completed her undergraduate studies in Genetics in the honors program at Rutgers University, where she received a Presidential scholarship. As an undergraduate student in the lab of Dr. Kim McKim she investigated spindle assembly factors in Drosophila oocytes and co-authored two manuscripts. Rachel joined the Snider lab in 2016 and her thesis project involves generation and characterization of a patient-derived model of Alexander Disease. She was awarded a Thermo Fisher Scientific Data Applications grant to develop a gene editing method to correct disease mutations in human induced pluripotent stem cells.
Helen has 35 years of laboratory experience leading various projects on animal models of disease, and is an expert on histology and microscopy techniques. She has over 20 publications that span multiple areas (pain, skeletal injury, development). In addition to planning and executing different liver injury studies, Helen trains students and fellows on laboratory techniques and manages the standard operating procedures in the lab to ensure compliance with IACUC and Environmental Health and Safety.
Rachel Battaglia, B.S.
Undergraduate Research Assistant